The specificity of interactions between proteins and sulfated polysaccharides

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The specificity of interactions between proteins and sulfated polysaccharides.

Sulfated polysaccharides are capable of binding with proteins at several levels of specificity. As highly acidic macromolecules, they can bind non-specifically to any basic patch on a protein surface at low ionic strength, and such interactions are not likely to be physiologically significant. On the other hand, several systems have been identified in which very specific substructures of sulfat...

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ژورنال

عنوان ژورنال: Anais da Academia Brasileira de Ciências

سال: 2005

ISSN: 0001-3765

DOI: 10.1590/s0001-37652005000400007